On on of our CFMX7 multi-server installs, we started getting these 2 errors when a customer tried to setup a MS Access DSN. Error 1

Unable to update the NT registry.Cannot open
HKEY_LOCAL_MACHINE\SOFTWARE\ODBC\ODBC.INI\ODBC Data Sources: Windows error
number 5 occurred. Access is denied. This error is actually caused by the user under which JRUN or ColdFusion MX runs under not having access to the specified registry key. This is most likely to happen if you are running the CFMX service under a user other than SYSTEM. Which was the case for me as our servers are locked down and secured and do not use any of the default install configurations. You need to edit the permissions on the ODBC key and give permission to all users under which your CFMX services run. Error 2

Unable to update the ColdFusion MX 7 ODBC Server.An error occurred when
performing a file operation WRITE on file
C:\JRun4\servers\\cfusion.ear\cfusion.war\WEB-INF\cfusion\db\slserver54\admin\xact.inp.The
cause of this exception was: java.io.FileNotFoundException:
C:\JRun4\servers\\cfusion.ear\cfusion.war\WEB-INF\cfusion\db\slserver54\admin\xact.inp
(The system cannot find the path specified). This one is caused by the non existence of the folder "slserver54". If you are running multiple instances, this folder is not copied by default when you create a new instance, so you will need to copy it over from the default "Cfusion" instance. the location where this folder should on your installation be is given in the error.